Getting Hold of the First Virus Ever Described !
Wendlandt T., Britz B., Kleinow T., Hipp K., Eber F.J., Wege C. (2024). Getting Hold of the Tobamovirus Particle - Why and How? Purification Routes over Time and a New Customizable Approach. Viruses, Special Issue "Tobamoviruses: Molecular Aspects and Resistance Regulation—a Special Issue Commemorating 125 Years of Research on Tobamoviruses" 16, 884. doi: 10.3390/v16060884
A fascinating walk through the ages of virus purification, with an extensive review of numerous methods for isolating biomolecular complexes throughout more than 125 years of research, and a novel advantageous procedure yielding ready-to-use particles for a plenitude of uses.
This article is dedicated to Holger Jeske (1952–2022), a scientific mentor, collaborator, and friend of TK, KH, and CW, and an encouraging discussion partner of FE and TW. He died way too early. He was a passionate, curious molecular plant virologist who perpetuated and advanced pioneering, historic experimental strategies into original current studies, inspiring us to work rigorously beyond conventional horizons. He has been an enthusiastic researcher primarily on Abutilon mosaic virus, regarded as essential for our current understanding of viruses, in parallel to his own and collaborative work with tobamoviruses. He enjoyed and promoted both classic approaches and novel technologies and supported the development of our research focus on tobamovirus-centered synthetic virology and nanobiotechnology in Stuttgart, for which he would have taken delight in co-authoring this article.
