The group 'Intelligent Biointegrative Systems' develops, tests and validates new biobased and biocompatible materials and processes for the application of generative manufacturing processes in life sciences in an interdisciplinary approach. To this end, the building blocks of life (proteins, lipid membranes and DNA) are structured into three-dimensional scaffolds and complex reaction spaces. All relevant length scales from the molecular scale to the cell and tissue level are integrated and combined with self-assembly and lithographic methods.
Our long-term goal is to achieve the most detailed (re-)construction of cellular structures and functional elements with the highest possible precision and controllability to advance our understandig of biomolecular and cell biological processes. This enables revolutionary new biomolecular structures and functions for applications in pharmaceutical, biotech and biomedical research, as well as in the production of tissue substitutes. In addition to new design methods for biomolecular process engineering, we are also developing new innovative methods for time-resolved sequence-structure-function analysis of biomolecular dynamics.