J. Brock, J. Erhardt, S.A. Eisler and M. Hörning
Cells, 11, 2122, 2022
Brief Summary: ''... Here, C2C12 myocytes were monitored on L-DOPA functionalized hydrogels of 22 different elasticity and fibronectin density compositions. We observed a fibronectin density independent increase of the projected cell area until 12 kPa and an optimal fibronectin density at about 2.6 μg/cm2 with a maximum actin filament to cell area ratio of 7.5%. The proliferation evaluation of cells showed an opposite correlation between cell spreading duration and speed to the matrix elasticity and protein density, which did not affect the cell cycle duration.''