8. Januar 2019 / Marcel Hörning

Hörning and Shibata 2019, Biophysical Journal

Three-dimensional cell geometry controls excitable membrane signaling in Dictyostelium cells

Three-dimensional cell geometry controls excitable membrane signaling in Dictyostelium cells 
M. Hörning and T. Shibata, Biophysical Journal, 116(2), 372-382, 2019
doi:  10.1016/j.bpj.2018.12.012
(BioRxiv, 278853, 2018  - doi : 10.1101/278853)

Brief Summary: ''... Using a novel method of three-dimensional analysis of the entire cell membrane of Dictyostelium cells, we found that PtdInsP3 domains can propagate persistently in any direction on the entire plasma membrane, while their propagation direction and speed are governed by the geometry of the cell. This study opens more general questions about how the system geometry and spatiotemporal signaling interact to control pattern dynamics. ...''

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