Dieses Bild zeigt Michael Heymann

Michael Heymann

Herr Jun.Prof. Dr.

Institut für Biomaterialien und biomolekulare Systeme
Abteilung Intelligente Biointegrative Systeme


Pfaffenwaldring 57
70569 Stuttgart
Raum: 9.555

  1. 2020

    1. Libicher, K., Hornberger, R., Heymann, M., & Mutschler, H. (2020). In vitro self-replication and multicistronic expression of large synthetic genomes. Nature Communications, 11(1), Article 1. https://doi.org/10.1038/s41467-020-14694-2
    2. Knoška, J., Adriano, L., Awel, S., Beyerlein, K. R., Yefanov, O., Oberthuer, D., Peña Murillo, G. E., Roth, N., Sarrou, I., Villanueva-Perez, P., Wiedorn, M. O., Wilde, F., Bajt, S., Chapman, H. N., & Heymann, M. (2020). Ultracompact 3D microfluidics for time-resolved structural biology. Nature Communications, 11(1), Article 1. https://doi.org/10.1038/s41467-020-14434-6
  2. 2019

    1. Jensen, S. C., Sullivan, B., Hartzler, D. A., Aguilar, J. M., Awel, S., Bajt, S., Basu, S., Bean, R., Chapman, H. N., Conrad, C., Frank, M., Fromme, R., Martin-Garcia, J. M., Grant, T. D., Heymann, M., Hunter, M. S., Ketawala, G., Kirian, R. A., Knoska, J., … Pushkar, Y. (2019). X ‑ ray Emission Spectroscopy at X ‑ ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis. The Journal of Physical Chemistry Letters, 10, 441--446. https://doi.org/10.1021/acs.jpclett.8b03595
    2. Katzmeier, F., Aufinger, L., Dupin, A., Quintero, J., Lenz, M., Bauer, L., Klumpe, S., Sherpa, D., Dürr, B., Honemann, M., Styazhkin, I., Simmel, F. C., & Heymann, M. (2019). A low-cost fluorescence reader for in vitro transcription and nucleic acid detection with Cas13a. PLOS ONE, 14(12), Article 12. https://doi.org/10.1371/journal.pone.0220091
    3. Hürtgen, D., Mascarenhas, J., Heymann, M., Murray, S. M., Schwille, P., & Sourjik, V. (2019). Reconstitution and Coupling of DNA Replication and Segregation in a Biomimetic System. ChemBioChem, 20, 2633–2642. https://doi.org/10.1002/cbic.201900299
    4. Yefanov, O., Oberthür, D., Bean, R., Wiedorn, M. O., Knoska, J., Pena, G., Awel, S., Gumprecht, L., Domaracky, M., Sarrou, I., Lourdu Xavier, P., Metz, M., Bajt, S., Mariani, V., Gevorkov, Y., White, T. A., Tolstikova, A., Villanueva-Perez, P., Seuring, C., … Barty, A. (2019). Evaluation of serial crystallographic structure determination within megahertz pulse trains. Structural Dynamics, 6(6), Article 6. https://doi.org/10.1063/1.5124387
    5. Weise, L. I., Heymann, M., Mayr, V., & Mutschler, H. (2019). Cell-free expression of RNA encoded genes using MS2 replicase. Nucleic Acids Research, 47(20), Article 20. https://doi.org/10.1093/nar/gkz817
    6. Bohne, S., Heymann, M., Chapman, H. N., Trieu, H. K., & Bajt, S. (2019). 3D printed nozzles on a silicon fluidic chip. Review of Scientific Instruments, 90(3), Article 3. https://doi.org/10.1063/1.5080428
    7. Fuest, M., Schaffer, M., Nocera, G. M., Galilea-Kleinsteuber, R. I., Messling, J.-E., Heymann, M., Plitzko, J. M., & Burg, T. P. (2019). In situ Microfluidic Cryofixation for Cryo Focused Ion Beam Milling and Cryo Electron Tomography. Scientific Reports, 9(1), Article 1. https://doi.org/10.1038/s41598-019-55413-2
    8. Eto, H., Soga, N., Franquelim, H. G., Glock, P., Khmelinskaia, A., Kai, L., Heymann, M., Noji, H., & Schwille, P. (2019). Design of Sealable Custom-Shaped Cell Mimicries Based on Self-Assembled Monolayers on CYTOP Polymer. ACS Applied Materials & Interfaces, 11(24), Article 24. https://doi.org/10.1021/acsami.9b05073
    9. Jia, H., Heymann, M., Härtel, T., Kai, L., & Schwille, P. (2019). Temperature-sensitive protein expression in protocells. Chem. Commun., 55(45), Article 45. https://doi.org/10.1039/C9CC02734C
  3. 2018

    1. Wang, Q., Taschner, M., Ganzinger, K. A., Kelley, C., Villasenor, A., Heymann, M., Schwille, P., Lorentzen, E., & Mizuno, N. (2018). Membrane association and remodeling by intraflagellar transport protein IFT172. Nature Communications, 9(1), Article 1. https://doi.org/10.1038/s41467-018-07037-9
    2. Litschel, T., Ramm, B., Maas, R., Heymann, M., & Schwille, P. (2018). Beating Vesicles: Encapsulated Protein Oscillations Cause Dynamic Membrane Deformations. Angewandte Chemie International Edition, 57(50), Article 50. https://doi.org/10.1002/anie.201808750
    3. Olmos, J. L., Pandey, S., Martin-Garcia, J. M., Calvey, G., Katz, A., Knoska, J., Kupitz, C., Hunter, M. S., Liang, M., Oberthuer, D., Yefanov, O., Wiedorn, M., Heymann, M., Holl, M., Pande, K., Barty, A., Miller, M. D., Stern, S., Roy-Chowdhury, S., … Schmidt, M. (2018). Enzyme intermediates captured ön the fly" by mix-and-inject serial crystallography. BMC Biology, 16(1), Article 1. https://doi.org/10.1186/s12915-018-0524-5
    4. Ramm, B., Glock, P., Mücksch, J., García soriano, D. A., Heymann, M., & Schwille, P. (2018). The MinDE system is a generic spatial cue for membrane protein distribution in vitro. Nature Communications, 9, 3942. https://doi.org/10.1038/s41467-018-06310-1
    5. Haiyang, J., Heymann, M., Bernhard, F., Schwille, P., & Kai, L. (2018). Cell free protein synthesis in micro compartments: building a minimal cell from bio bricks. submitted.
    6. Gicquel, Y., Schubert, R., Kapis, S., Bourenkov, G., Schneider, T., Perbandt, M., Betzel, C., Chapman, H. N., & Heymann, M. (2018). Microfluidic chips for in situ crystal X-ray diffraction and in situ dynamic light scattering for serial crystallography. Journal of Visualized Experiments, 134, Article 134. https://doi.org/10.3791/57133
    7. Litschel, T., Ganzinger, K. A., Movinkel, T., Heymann, M., Robinson, T., Mutschler, H., & Schwille, P. (2018). Freeze-thaw cycles induce content exchange between cell-sized lipid vesicles Freeze-thaw cycles induce content exchange between cell-sized lipid vesicles. New Journal of Physics, 055008, 11. https://doi.org/10.1088/1367-2630/aabb96
    8. Jia, H., Kai, L., Heymann, M., Garcia-Soriano, D. A., Härtel, T., & Schwille, P. (2018). Light-Induced Printing of Protein Structures on Membranes in Vitro ̈. Nano Letters, 18, 7133--7140. https://doi.org/10.1021/acs.nanolett.8b03187
    9. Wiedorn, M. O., Oberthür, D., Bean, R., Schubert, R., Werner, N., Abbey, B., Aepfelbacher, M., Adriano, L., Allahgholi, A., Al-Qudami, N., Andreasson, J., Aplin, S., Awel, S., Ayyer, K., Bajt, S., Barák, I., Bari, S., Bielecki, J., Botha, S., … Barty, A. (2018). Megahertz serial crystallography. Nature Communications, 9(1), Article 1. https://doi.org/10.1038/s41467-018-06156-7
    10. Niederauer, C., Blumhardt, P., Mücksch, J., Heymann, M., Lambacher, A., & Schwille, P. (2018). Direct characterization of the evanescent field in objective-type total internal reflection fluorescence microscopy. Optics Express, 26(16), Article 16. https://doi.org/10.1364/OE.26.020492
    11. Wiedorn, M. O., Awel, S., Morgan, A. J., Ayyer, K., Gevorkov, Y., Fleckenstein, H., Roth, N., Adriano, L., Bean, R., Beyerlein, K. R., Chen, J., Coe, J., Cruz-Mazo, F., Ekeberg, T., Graceffa, R., Heymann, M., Oberthür, D., Samanta, A. K., Sierra, R. G., … Chapman, H. N. (2018). Rapid sample delivery for megahertz serial crystallography at X-ray FELs. IUCrJ, 5, 574--584. https://doi.org/10.1107/S2052252518008369
  4. 2017

    1. Wojtas, D. H., Ayyer, K., Liang, M., Mossou, E., Romoli, F., Seuring, C., Beyerlein, K. R., Bean, R. J., Morgan, A. J., Oberthuer, D., Fleckenstein, H., Heymann, M., Gati, C., Yefanov, O. M., Barthelmess, M., Ornithopoulou, E., Galli, L., Xavier, P. L., Ling, W. L., … Millane, R. P. (2017). Analysis of XFEL serial diffraction data from individual crystalline fibrils. IUCrJ, 4(6), Article 6. https://doi.org/10.1107/S2052252517014324
    2. Rambach, R. W., Linder, K., Heymann, M., & Franke, T. (2017). Droplet trapping and fast acoustic release in a multi-height device with steady-state flow. Lab on a Chip, 17(20), Article 20. https://doi.org/10.1039/c7lc00378a
    3. Jia, H., Heymann, M., Bernhard, F., Schwille, P., & Kai, L. (2017). Cell-free protein synthesis in micro compartments: Building a minimal cell from biobricks. New Biotechnology. https://doi.org/10.1016/j.nbt.2017.06.014
    4. Beyerlein, K. R., Dierksmeyer, D., Mariani, V., Kuhn, M., Sarrou, I., Ottaviano, A., Awel, S., Knoska, J., Fuglerud, S., Jönsson, O., Stern, S., Wiedorn, M. O., Yefanov, O., Adriano, L., Bean, R., Burkhardt, A., Fischer, P., Heymann, M., Horke, D. A., … Oberthuer, D. (2017). Mix-and-diffuse serial synchrotron crystallography. IUCrJ, 4. https://doi.org/10.1107/S2052252517013124
    5. Wiedorn, M. O., Awel, S., Morgan, A. J., Barthelmess, M., Bean, R., Beyerlein, K. R., Chavas, L. M. G., Eckerskorn, N., Fleckenstein, H., Heymann, M., Horke, D. A., Knoska, J., Mariani, V., Oberthür, D., Roth, N., Yefanov, O., Barty, A., Bajt, S., Küpper, J., … Chapman, H. N. (2017). Post-sample aperture for low background diffraction experiments at X-ray free-electron lasers. Journal of Synchrotron Radiation, 24(6), Article 6. https://doi.org/10.1107/S1600577517011961
    6. Oberthuer, D., Knoska, J., Wiedorn, M. O., Beyerlein, K. R., Bushnell, D. A., Kovaleva, E. G., Heymann, M., Gumprecht, L., Kirian, R. A., Barty, A., Mariani, V., Tolstikova, A., Adriano, L., Awel, S., Barthelmess, M., Dörner, K., Xavier, P. L., Yefanov, O. M., James, D., … Bajt, S. (2017). Double-flow focused liquid injector for efficient serial femtosecond crystallography. Scientific Reports, 7(1), Article 1. https://doi.org/10.1038/srep44628
    7. Aghvami, S. A., Opathalage, A., Zhang, Z. K., Ludwig, M., Heymann, M., Norton, M., Wilkins, N., & Fraden, S. (2017). Rapid prototyping of cyclic olefin copolymer (COC) microfluidic devices. Sensors and Actuators, B: Chemical, 247. https://doi.org/10.1016/j.snb.2017.03.023
  5. 2016

    1. Nelson, G., Kirian, R. A. R. A., Weierstall, U., Zatsepin, N. A., Faragó, T., Baumbach, T., Wilde, F., Niesler, F. B. P., Zimmer, B., Ishigami, I., Hikita, M., Bajt, S., Yeh, S.-R., Rousseau, D. L., Chapman, H. N., Spence, J. C. H., & Heymann, M. (2016). Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery. Optics Express, 24(11), Article 11. https://doi.org/10.1364/OE.24.011515
    2. Schubert, R., Kapis, S., Gicquel, Y., Bourenkov, G., Schneider, T. R. T. R., Heymann, M., Betzel, C., & Perbandt, M. (2016). A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution. IUCrJ, 3, 393--401. https://doi.org/10.1107/S2052252516016304
    3. Wang, A. L. L., Gold, J. M. M., Tompkins, N., Heymann, M., Harrington, K. I. I., & Fraden, S. (2016). Configurable NOR gate arrays from. European Physical Journal, 225(1), Article 1. https://doi.org/10.1140/epjst/e2016-02622-y
  6. 2015

    1. Tompkins, N., Cambria, M. C., Wang, A. L., Heymann, M., & Fraden, S. (2015). Creation and perturbation of planar networks of chemical oscillators. Chaos, 25(6), Article 6. https://doi.org/10.1063/1.4922056
    2. Chen, D. T. N., Heymann, M., Fraden, S., Nicastro, D., & Dogic, Z. (2015). ATP Consumption of Eukaryotic Flagella Measured at a Single-Cell Level. Biophysical Journal, 109(12), Article 12. https://doi.org/10.1016/j.bpj.2015.11.003
    3. Kirian, R. A., Awel, S., Eckerskorn, N., Fleckenstein, H., Wiedorn, M., Adriano, L., Bajt, S., Barthelmess, M., Bean, R., Beyerlein, K. R., Chavas, L. M. G., Domaracky, M., Heymann, M., Horke, D. a., Knoska, J., Metz, M., Morgan, A., Oberthuer, D., Roth, N., … Chapman, H. N. (2015). Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers. Structural Dynamics, 2(4), Article 4. https://doi.org/10.1063/1.4922648
    4. Beyerlein, K. R., Adriano, L., Heymann, M., Kirian, R. A., Knoska, J., Wilde, F., Chapman, H. N., Knoska, J., Wilde, F., Chapman, H. N., & Bajt, S. (2015). Ceramic micro-injection molded nozzles for serial femtosecond crystallography sample delivery. Review of Scientific Instruments, 86(12), Article 12. https://doi.org/10.1063/1.4936843
    5. Feld, G. K., Heymann, M., Benner, W. H., Pardini, T., Tsai, C.-J., Boutet, S., Coleman, M. A., Hunter, M. S., Li, X.-D. X., Messerschmidt, M., Opthalage, A., Pedrini, B., Williams, G. J., Krantz, B. A., Fraden, S., Hau-Riege, S. P., Evans, J. E., Segelke, B. W., Frank, M., … Frank, M. (2015). Low- Z polymer sample supports for fixed-target serial femtosecond X-ray crystallography. Journal of Applied Crystallography, 48(4), Article 4. https://doi.org/10.1107/S1600576715010493
    6. Nogly, P., James, D., Wang, D., White, T. a., Zatsepin, N., Shilova, A., Nelson, G., Liu, H., Johansson, L., Heymann, M., Jaeger, K., Metz, M., Wickstrand, C., Wu, W., B\aath, P., Berntsen, P., Oberthuer, D., Panneels, V., Cherezov, V., … Weierstall, U. (2015). Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. IUCrJ, 2(2), Article 2. https://doi.org/10.1107/S2052252514026487
  7. 2014

    1. Tompkins, N., Li, N., Girabawe, C., Heymann, M., Ermentrout, G. B., Epstein, I. R., & Fraden, S. (2014). Testing Turing’s theory of morphogenesis in chemical cells. PNAS, 111(12), Article 12. https://doi.org/10.1073/pnas.1322005111
    2. Tenboer, J., Basu, S., Zatsepin, N., Pande, K., Milathianaki, D., Frank, M., Hunter, M., Boutet, S., Williams, G. J., Koglin, J. E., Oberthuer, D., Heymann, M., Kupitz, C., Conrad, C., Coe, J., Roy-Chowdhury, S., Weierstall, U., James, D., Wang, D., … Schmidt, M. (2014). Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein. Science, 346(6214), Article 6214. https://doi.org/10.1126/science.1259357
    3. Kornreich, M., Heymann, M., Fraden, S., & Beck, R. (2014). Cross polarization compatible dialysis chip. Lab on a chip, 14(19), Article 19. https://doi.org/10.1039/c4lc00600c
    4. Akella, S. V., Mowitz, A., Heymann, M., & Fraden, S. (2014). Emulsion-Based Technique To Measure Protein Crystal Nucleation Rates of Lysozyme. Crystal Growth and Design, 14, 4487--4509. https://doi.org/10.1021/cg500562r
    5. Heymann, M., Opthalage, A., Wierman, J. L., Akella, S., Szebenyi, D. M. E., Gruner, S. M., & Fraden, S. (2014). Room-temperature serial crystallography using a kinetically optimized microfluidic device for protein crystallization and on-chip X-ray diffraction. IUCrJ, 1(5), Article 5. https://doi.org/10.1107/S2052252514016960
  8. 2013

    1. Heymann, M., Fraden, S., & Kim, D. (2013). Multi-Height Precision Alignment With Selectively Developed Alignment Marks. Journal of Microelectromechanical Systems, 23(2), Article 2. https://doi.org/10.1109/JMEMS.2013.2279231
  9. 2012

    1. Sanchez, T., Chen, D. T. N., DeCamp, S. J., Heymann, M., & Dogic, Z. (2012). Spontaneous motion in hierarchically assembled active matter. Nature, 491(7424), Article 7424. https://doi.org/10.1038/nature11591
  10. 2010

    1. Heymann, M., Harrington, K. I., Pollack, J., & Fraden, S. (2010). En Route to Signal Inversion in Chemical Computing. Proceedings of Artificial Life XII, 166--167.
    2. Romanowsky, M. B., Heymann, M., Abate, A. R., Krummel, A. T., Fraden, S., & Weitz, D. A. (2010). Functional patterning of PDMS microfluidic devices using integrated chemo-masks. Lab on a chip, 10(12), Article 12. https://doi.org/10.1039/c004050a
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